They postulate that this may be due to co-occurrence or to overlapping pathogenesis. Regarding the latter, they suggest that enthesopathy may be the pathogenic feature common to both illnesses. Enthesitis is thought to play a primary role in psoriatic arthritis, 2 and imaging studies have demonstrated enthesopathy even in psoriasis patients who do not have clinical arthritis.
As PsA is also entheseal related, it is not surprising that differentiation between it and OA can be impossible. Epidemiology is similar and therefore not a differentiating factor since both PsA and OA are more common after the age of Interestingly, this is also when entheseal age-related changes are present. Clinical presentation is often similar as well, and both diseases can involve the same joints. McGonagle et al noted that both OA and PsA can affect the cervical and lumbar spine, distal and PIP hand joints, knees, and first metatarsophalangeal joints.
However, OA is more likely to affect the hips and carpometacarpal joints, and PsA is more likely to affect metacarpophalangeal joints, ankles, and toes. Even the presence of inflammation, a hallmark of PsA, fails to differentiate many cases of OA and PsA, according to the authors.
Founded in , the Arthritis Center at Johns Hopkins is dedicated to providing quality education to patients and healthcare providers alike. Question What is the difference between Osteoarthritis and Psoriatic Arthritis? Rheumatoid arthritis is an autoimmune disease, which means that the immune system malfunctions and attacks the body instead of intruders. In this case, it attacks the synovial membrane that encases and protects the joints.
Rheumatoid arthritis often targets several joints at one time. The symptoms of rheumatoid arthritis include:. For more details about these two different types of arthritis, please visit our Rheumatoid arthritis page and our Osteoarthritis page. The biggest difference is the joints involved in the hands and feet and the fact that psoriatic arthritis also involves psoriasis of the skin which is a persistent chronic disease in itself.
Psoriasis causes itchy, dry, red patches and thick silvery scales of the skin that can sometimes be painful and embarrassing!
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